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Human coronavirus OC43 : ウィキペディア英語版
Human coronavirus OC43

Human coronavirus OC43 is an enveloped, positive-sense, single-stranded RNA virus species in the ''Betacoronavirus'' genus, of the subfamily ''Coronavirinae'', in the family ''Coronaviridae'', of the order ''Nidovirales''.
==Virology==
Four HCoV-OC43 genotypes (A to D), have been identified with genotype D most likely arising from recombination. The complete genome sequencing of two genotype C and D strains and bootscan analysis shows recombination events between genotypes B and C in the generation of genotype D. Of 29 strains identified, none belong to the more ancient genotype A. Molecular clock analysis using spike and nucleocapsid genes dates the most recent common ancestor of all genotypes to the 1950s. Genotype B and C date to the 1980s. Genotype B to the 1990s, and genotype C to the late 1990s to early 2000s. The recombinant genotype D strains were detected as early as 2004.〔

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